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Peering Into American Airlines Gr's Recent Short InterestAndre Drummond latest 76er to hit the injury listAnalysis: Protecting QBs from violent late hits like the one that leveled Trevor Lawrence isn't easy
CAPE CANAVERAL, Fla. (AP) — Known across the globe as the stuck astronauts, Butch Wilmore and Suni Williams hit the six-month mark in space Thursday with two more to go. The pair rocketed into orbit on June 5, the first to ride Boeing’s new Starliner crew capsule on what was supposed to be a weeklong test flight. They arrived at the International Space Station the next day, only after overcoming a cascade of thruster failures and helium leaks . NASA deemed the capsule too risky for a return flight, so it will be February before their long and trying mission comes to a close. While NASA managers bristle at calling them stuck or stranded, the two retired Navy captains shrug off the description of their plight. They insist they’re fine and accepting of their fate. Wilmore views it as a detour of sorts: “We’re just on a different path.” “I like everything about being up here,” Williams told students Wednesday from an elementary school named for her in Needham, Massachusetts, her hometown. "Just living in space is super fun.” Both astronauts have lived up there before so they quickly became full-fledged members of the crew, helping with science experiments and chores like fixing a broken toilet, vacuuming the air vents and watering the plants. Williams took over as station commander in September. “Mindset does go a long way,” Wilmore said in response to a question from Nashville first-graders in October. He’s from Mount Juliet, Tennessee. “I don’t look at these situations in life as being downers.” Boeing flew its Starliner capsule home empty in September, and NASA moved Wilmore and Williams to a SpaceX flight not due back until late February. Two other astronauts were bumped to make room and to keep to a six-month schedule for crew rotations. Like other station crews, Wilmore and Williams trained for spacewalks and any unexpected situations that might arise. “When the crews go up, they know they could be there for up to a year,” said NASA Associate Administrator Jim Free. NASA astronaut Frank Rubio found that out the hard way when the Russian Space Agency had to rush up a replacement capsule for him and two cosmonauts in 2023, pushing their six-month mission to just past a year. Boeing said this week that input from Wilmore and Williams has been “invaluable" in the ongoing inquiry of what went wrong. The company said in a statement that it is preparing for Starliner's next flight but declined comment on when it might launch again. NASA also has high praise for the pair. “Whether it was luck or whether it was selection, they were great folks to have for this mission,” NASA's chief health and medical officer, Dr. JD Polk, said during an interview with The Associated Press. On top of everything else, Williams, 59, has had to deal with “rumors,” as she calls them, of serious weight loss. She insists her weight is the same as it was on launch day, which Polk confirms. During Wednesday's student chat, Williams said she didn't have much of an appetite when she first arrived in space. But now she's “super hungry” and eating three meals a day plus snacks, while logging the required two hours of daily exercise. Williams, a distance runner, uses the space station treadmill to support races in her home state. She competed in Cape Cod’s 7-mile Falmouth Road Race in August. She ran the 2007 Boston Marathon up there as well. She has a New England Patriots shirt with her for game days, as well as a Red Sox spring training shirt. “Hopefully I’ll be home before that happens -- but you never know,” she said in November. Husband Michael Williams, a retired federal marshal and former Navy aviator, is caring for their dogs back home in Houston. As for Wilmore, 61, he's missing his younger daughter's senior year in high school and his older daughter's theater productions in college. “We can’t deny that being unexpectedly separated, especially during the holidays when the entire family gets together, brings increased yearnings to share the time and events together,” his wife, Deanna Wilmore, told the AP in a text this week. Her husband “has it worse than us” since he's confined to the space station and can only connect via video for short periods. “We are certainly looking forward to February!!” she wrote. The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
BERKELEY HEIGHTS, N.J., Dec. 05, 2024 (GLOBE NEWSWIRE) -- Cyclacel Pharmaceuticals, Inc. (NASDAQ: CYCC, NASDAQ: CYCCP; "Cyclacel" or the "Company"), a biopharmaceutical company developing innovative cancer medicines, today announced that it is in the process of exploring and reviewing strategic alternatives on an expedited basis in order to preserve the Company’s cash, including a potential transaction with investor David Lazar of Activist Investing, LLC, which transaction would be subject to the consent of an existing securityholder. The Company’s Board of Directors is reviewing a range of appropriate strategies to realize value from its assets. The Board has directed management to reduce operating costs while such alternatives are being explored. There can be no assurance that the exploration of strategic alternatives will result in any agreement or transaction, or as to the timing of any such agreement or transaction. Further, there can be no assurance that the Company will be able to reach an agreement, or consummate a transaction, with Mr. Lazar or receive the required consent of an existing securityholder to any such transaction. As previously disclosed, the Company does not presently meet the continued listing requirements of the Nasdaq Stock Market and its securities would be subject to delisting if the Company fails to regain compliance during the required compliance period. In the event that the Company is not able to enter into a strategic transaction and/or secure additional funding, it may be forced to cease all business operations. In such event, the Company’s stockholders may lose a part or all of their investment in the Company. About Cyclacel Pharmaceuticals, Inc. Cyclacel is a clinical-stage, biopharmaceutical company developing innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis biology. The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program plogosertib, a PLK1 inhibitor, in patients with both solid tumors and hematological malignancies. Cyclacel's strategy is to build a diversified biopharmaceutical business based on a pipeline of novel drug candidates addressing oncology and hematology indications. For additional information, please visit www.cyclacel.com. Forward-looking Statements This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include, among other things, statements related to the Company’s exploration and review of strategic alternatives, its ability to identify and complete a transaction as a result of the strategic review process, including a potential transaction with David Lazar, its plans to reduce costs and conserve cash and Cyclacel’s ability to regain and maintain compliance with Nasdaq’s continued listing requirements. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "potential," "expects," "plans," "anticipates," "intends," "continues," "forecast," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. These risks and uncertainties include the risk that the Company may not be successful in exploring strategic alternatives and consummating one or more strategic transactions on attractive terms, if at all; the Company’s actual reductions in spending as compared to anticipated cost reductions; the Company’s costs of continuing to operate as a public company; and the other risks described more fully in Cyclacel Pharmaceuticals’ filings with the Securities and Exchange Commission, including the “Risk Factors” section of the Company’s Annual Report on Form 10-K for the year ending December 31, 2023 and its other documents subsequently filed with or furnished to the Securities and Exchange Commission, including its Form 10-Q for the quarter ended September 30, 2024. For a further list and description of the risks and uncertainties the Company faces, please refer to our most recent Annual Report on Form 10-K and other periodic and other filings we file with the Securities and Exchange Commission and are available at www.sec.gov . Such forward-looking statements are current only as of the date they are made, and we assume no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. Contacts Company: Paul McBarron, (908) 517-7330, IR@cyclacel.com © Copyright 2024 Cyclacel Pharmaceuticals, Inc. All Rights Reserved. The Cyclacel logo and Cyclacel® are trademarks of Cyclacel Pharmaceuticals, Inc.
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EDITOR'S NOTE: On Football analyzes the biggest topics in the NFL from week to week. No one wants to see any player take a vicious hit like the one that knocked Trevor Lawrence out of the game. It’s easy to agree on that point. Eliminating violent shots is the hard part. The NFL has instituted several rules to protect quarterbacks but football is a physical sport and players have to react instantly and make split-second decisions going at high speeds so injuries keep occurring. Lawrence was carted off the field in the first half of Jacksonville’s 23-20 loss to Houston on Sunday after Azeez Al-Shaair leveled the defenseless quarterback with a forearm to the facemask. The late hit put Lawrence in the fencing position — both fists clenched — and he stayed on the ground for several minutes, while a brawl ensued. Lawrence didn’t require hospitalization for his concussion but it’s unknown when he’ll return. “Thank you to everyone who has reached out/been praying for me,” Lawrence wrote on X. “I’m home and feeling better. Means a lot, thank you all.” Al-Shaair was ejected from the game and faces a fine and potential suspension after his latest unsportsmanlike penalty. The Texans' linebacker was flagged and later fined $11,255 for a late hit out of bounds on Titans running back Tony Pollard last week. He was fined earlier this year after he punched Bears running back Roschon Johnson on the sideline in Week 2. That occurred during a scuffle that started after his hard shot on quarterback Caleb Williams near the sideline that wasn’t flagged. Al-Shaair once got away with grabbing Tom Brady by the throat on a pass rush in a game between the 49ers and Buccaneers. Outraged Jaguars players called Al-Shaair’s hit “dirty” and Texans coach DeMeco Ryans made it known he didn’t condone it. “It’s not what we’re coaching,” Ryans said. “Want to be smart in everything we do and not hurt the team, get a penalty there. Have to be smarter when the quarterback is going down. Unfortunate play. Not representative of who Azeez is. He’s a smart player, really great leader for us. We felt his presence not being there. His loss really affected us on the defensive side. Just not what we’re coaching. Didn’t want to see the melee and all the aftermath. That’s not what we’re about. Not representative of us. I’ll talk to Azeez, address him personally, and we’ll move forward from it.” Fox Sports color analyst Daryl Johnston, a former fullback for the Dallas Cowboys, didn’t hold back his criticism, calling it a “cheap shot.” “It’s everything you’re not supposed to do,” Johnston said. “Everything. You’ll see this in slow motion and Azeez Al-Shaair does everything you’re trying to prevent in this situation. It’s reckless. It’s disrespectful. There’s an honor that you give to your opponent on the football field and you respect him. And there’s opportunities to be physical and give big hits and play this game in that manner. And there’s other times when there’s a respect that you grant to your opponent.” Some former NFL quarterbacks blasted Al-Shaair on social media. “There is no place in the game of football for dirty hits like this one,” Robert Griffin III wrote on X. Chase Daniel called it “one of the dirtiest hits” he’s ever seen on a quarterback. Even defensive players struggled to defend Al-Shaair. “That was uncalled for,” Hall of Fame defensive lineman Michael Strahan said on Fox’s studio show while fellow Hall of Famer Howie Long agreed. But the play also sparked debate about the quarterback slide. Lawrence slid feet first, which signals that he’s giving himself up on the play. The NFL rulebook states: “A defender must pull up when a runner begins a feet-first slide.” But defensive players aren’t automatically penalized if they make contact with a sliding quarterback if they already committed and the contact is unavoidable. The rules state it’s a foul when “the defender makes forcible contact into the head or neck area of the runner with the helmet, shoulder, or forearm, or commits some other act that is unnecessary roughness.” Al-Shaair did that so he was penalized and will face other repercussions. Still, given the hard-hitting nature of the sport, it won’t be the last time this happens.